If you are the googler who searched for this: "what happens if you are having trouble with a friend and she is my best friend what do u do" and you ended up with my site as the number one hit, I am sorry you will not find the answers here. I'm not a psychologist, nor am I related to Ann Landers. I'm just a blogger.
There's an idea: maybe you should start a blog. I did, and now I have lots of friends. Haven't pissed too many of them off, either, so that's good. (But it would help if you learned the difference between first person, second person, and third person usage and use them consistently.)